Bahrain will suspend dine-in services at restaurants and cafes and move public and private schools to remote learning for three weeks to contain the spread of the coronavirus, the health ministry said.
It said it had detected a new variant of coronavirus in a number of cases, without specifying which kind.
The new lockdown measures will come into effect on Sunday.
There has been an uptick in coronavirus cases in the Gulf kingdom since December. The country registered 459 new cases on Wednesday, adding to a total of nearly 100,000 since the start of the pandemic, with 370 deaths.
The small island state has the third highest rate of vaccinations per capita in the world so far, according to the Our World in Data website, which is run by an Oxford University research programme.
Bahrain offers its citizens either the Pfizer/BioNTech vaccine or one manufactured by Chinese state-backed pharmaceutical giant Sinopharm free of charge.
The kingdom also approved the AstraZeneca COVID-19 vaccine on Monday for emergency use.
Russia has opened a criminal case against Ukrainian President Volodymyr Zelenskiy and put him on a wanted list, the state news agency TASS reported on Saturday, citing the Interior Ministry's database.
The death toll from rains in Brazil's southernmost state of Rio Grande do Sul rose to 56, local authorities said on Saturday morning, while dozens still have not been accounted for.
Hamas has said it is sending a delegation to Cairo on Saturday to discuss a deal for a truce and the release of hostages in Gaza, hours after US CIA Director William Burns arrived in the Egyptian capital, according to Egyptian sources.
NATO's four-month long military exercises near Russia's borders, known as Steadfast Defender, are proof the alliance is preparing for a potential conflict with Russia, a spokeswoman for Russia's Foreign Ministry said on Saturday.
The President His Highness Sheikh Mohamed bin Zayed Al Nahyan has received condolences from regional leaders on the death of his uncle, Sheikh Tahnoun bin Mohammed Al Nahyan.