England bowled West Indies out for 45 - the second lowest total in international Twenty20 history - to win by 137 runs in St Kitts.
Joe Root's 55 runs and Sam Billings' brilliant knock of 87 off 47 balls helped to win with ease, taking an unassailable 2-0 lead in the series.
This is England's biggest margin of victory by runs in T20s and the fourth biggest of all time.
The final T20 will be played in St Kitts at 20:00 GMT on Sunday.
Coventry promoted to Premier League after 25-year absence
Coventry City ended their 25-year absence from the Premier League with a 1-1 draw at Blackburn Rovers, securing promotion from the Championship with three games to spare on Friday.
Gujarat sink Kolkata with adaptable bowling in IPL
Gujarat Titans adapted to conditions to secure a five-wicket win over Kolkata Knight Riders on Friday, fast bowler Kagiso Rabada said, focusing on tight bowling instead of the explosive batting that has been the hallmark of the Indian Premier League.
Alcaraz pulls out of Madrid Open for second straight year
Carlos Alcaraz will miss the Madrid Open for the second consecutive year after withdrawing on Friday with a wrist injury, dealing another blow to the world number two's clay court preparations ahead of his French Open title defence.
Injured Djokovic to miss Madrid Open
Novak Djokovic is still working through the injury problems that forced him to miss recent tournaments in Miami and Monte Carlo and said on Friday that he will not feature at next week's Madrid Open, one of the last stops before the French Open.
Mumbai's IPL campaign fizzles amid Bumrah's barren run
Mumbai Indians head coach Mahela Jayawardene has defended Jasprit Bumrah after the struggling pace spearhead went a fifth Indian Premier League match without a wicket in Thursday's seven-wicket defeat by Punjab Kings.
Bus operations for public and private schools in the UAE will resume on Monday, April 20.
Dubai Police, in collaboration with the UAE Ministry of Interior, have arrested an Irish fugitive accused of involvement in an organised criminal group linked to international crimes in his home country.
UAE President His Highness Sheikh Mohamed bin Zayed Al Nahyan has met with His Highness Sheikh Hamad bin Mohammed Al Sharqi, Supreme Council Member and Ruler of Fujairah, to discuss national priorities and the country’s continued development.
