Jason Roy and captain Joe Root both smashed centuries as the tourists easily reached their target of 361 with eight balls to spare in Barbados.
It was their highest ever run-chase in the format.
Chris Gayle's innings of 139 off 129 balls went in vain as the Windies' poor form in ODI cricket continued.
The second encounter of the five-match series will be played on Friday.
Troubled Marseille lose fifth straight as PSG win
Captain Marquinhos has snatched the winner as champions Paris St Germain won 2-1 at troubled Olympique de Marseille in Ligue 1 on Sunday, condemning the hosts to a fifth successive loss and a spot in the relegation zone.
Anders Dreyer’s brace earns San Diego road draw with Inter Miami
Anders Dreyer has scored his 10th and 11th goals on either side of halftime and visiting San Diego FC earned a 2-2 draw against Lionel Messi and defending MLS Cup champions Inter Miami on Sunday night.
Man City beat Sunderland in thriller to maintain 100% start
Manchester City head into the first international break three points clear at the top of the Premier League after Antoine Semenyo's double sealed an enthralling 5-3 home win over Sunderland, for whom Brian Brobbey grabbed a hat-trick, on Sunday.
Spaun uses Presidents Cup snub to win BMW PGA Championship
JJ Spaun had a message for US Presidents Cup captain Brandt Snedeker, and he delivered it with his clubs instead of his phone, closing with a hot finish to win the BMW PGA Championship on Sunday in Surrey, England.
Atletico ride derby storm to beat 10-man Real Madrid 2-1
Atletico Madrid beat arch-rivals Real Madrid 2-1 in LaLiga on Sunday as second-half goals from Alejandro Grimaldo and Jonathan David settled a tense derby at a packed Estadio Metropolitano.
The UAE, working with Paraguay, has sent humanitarian supplies to communities affected by the earthquake in Colombia as part of a $10 million aid package.
The UAE has called for a more inclusive international approach to combating extremism and hate speech, with greater involvement from community leaders, young people, civil society and technology companies.
Four UAE humanitarian aid convoys entered the Gaza Strip over the past week carrying 781 tonnes of supplies as part of Operation Chivalrous Knight 3.
