According to manager Ole Gunnar Solskjaer, the France midfielder needs an operation on his ankle.
The 26-year-old only made his comeback last month, as his ankle problem kept him out since late September last year.
Scott McTominay is currently also out injured.
Pogba has played only eight times this season after having surgery to correct another ankle injury.
Pogacar wins record-equalling fifth Tour de France title
UAE Team Emirates-XRG rider Tadej Pogacar secured a record-equalling fifth Tour de France title on Sunday after safely navigating the final stage, won by Mathieu van der Poel, to seal a third consecutive crown in cycling's greatest race.
Herbert storms to record-breaking LIV Golf UK victory
Australia's Lucas Herbert claimed the LIV Golf United Kingdom title in record-breaking fashion, firing a final-round 62 to finish on 30-under-par and secure a six-shot victory at JCB Golf & Country Club in England.
India’s prodigy Sooryavanshi leads the way in T20 series success
India’s teenage prodigy Vaibhav Sooryavanshi blasted an impressive 81 runs on Sunday to steer his side to a 3-0 whitewash of hosts Zimbabwe in their Twenty20 series at the Harare Sports Club.
Norris wins Hungarian Grand Prix for McLaren
Formula One champion Lando Norris won the Hungarian Grand Prix for McLaren's first victory of the season on Sunday while Mercedes's Kimi Antonelli extended his overall lead to 50 points.
Abu Dhabi UFC Fight Night ends with Ankalaev fifth-round victory
Magomed Ankalaev secured a fifth-round stoppage victory over Bogdan Guskov at UFC Fight Night in Abu Dhabi on Saturday after overcoming a slow start to strengthen his claim for a shot at the UFC light heavyweight title.
The UAE has strongly condemned attacks by Israeli settlers on villages in the occupied West Bank, calling on the Israeli government to hold those responsible accountable.
The United Arab Emirates Deputy Prime Minister and Minister of Foreign Affairs Sheikh Abdullah bin Zayed Al Nahyan has discussed regional developments with his counterparts from Qatar and Oman.
The UAE has expressed its solidarity with France as devastating wildfires continue to sweep across the country's southwest, forcing the evacuation of around 220,000 people and threatening the outskirts of Bordeaux.
